Home » Prescription Drugs 5 » DACARB Generic Dacarbazine
Dacarbazine is an anticancer (cytotoxic) medicine.Cancers form when some cells within the body multiply uncontrollably and abnormally. There are two types of cancer. Solid cancers where a lump forms e.g. the bone muscle brain cells etc. divide and multiply abnormally. The second type are leukaemias and lymphomas where the blood cells divide and multiply abnormally.Other characteristics of cancer besides uncontrolled growth include the ability of these abnormal cells to invade other tissues next to them or to break away from the original site travel through the blood or lymph and establish a new cancer at a different site of the body. These are called metastases.Like normal healthy cells cancer cells go through a continuous process of change. Each cell divides into two daughter cells. These cells grow rest and then divide again. The medicines used in chemotherapy are powerful chemicals designed to interupt this cycle and stop cells from growing.Several different types of anticancer medicines are used in chemotherapy. Each type kills cells at a different stage of the cell's life cycle. Each does its job in a different way.Dacarbazine is a synthetic compound. It works by blocking the production of genetic material (DNA) in the cell by binding it together. This prevents the cell from growing and therefore it dies.Unfortunately anticancer medicines will also affect the growth and division of normal healthy cells in the same way such as blood gut and hair cells. This can therefore cause several of the side effects seen with chemotherapy e.g. hair loss. The body's immune system also becomes suppressed increasing the risk of infections.In most chemotherapy regimens doses are administered in courses at various intervals to allow normal cells to recover from the adverse effects of the anticancer medicines between doses. However during this period cancer cells will also recover and start to replicate again. Successful treatment depends on the administration of the next course of therapy before the cancer has regrown to its previous size and the net effect is to decrease the amount of cancer with each successive course.Dacarbazine is used in combination with other anticancer medicines. It is administered by intravenous infusion.What is it used for?Breast cancer Cancer of the colon (large bowel) Cancer of the ovaries Cancer of the soft tissue e.g. muscle (soft tissue sarcoma)Lung cancer Lymph node cancer (Hodgkin's disease) Metastatic cancerous melanoma Testicular cancer
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About DACARB Generic Dacarbazine:
Product Type: Prescription Drugs 5
DACARB ( Generic Dacarbazine )
DACARB (Generic Dacarbazine)
Generic Dacarbazine
200MG 16 Tablets
Generic Dacarbazine DACARB

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Medicine News : The first transgenic mouse model of a rare and severe type of autism called Timothy Syndrome is improving the scientific understanding of autism spectrum disorder in general and may help researchers design more targeted interventions and treatments. The research is described in a paper published last week by scientists at the University at Buffalo and Stanford University in the Proceedings of the National Academy of Sciences.
The transgenic mouse developed at UB exhibits the repetitive physical behaviors, altered social behaviors and impaired communication abilities associated not just with Timothy Syndrome but with autism spectrum disorder in general.
The fact that this mouse exhibited so many behavioral parallels with humans diagnosed with autism was both surprising and encouraging, the researchers say.
"This animal and the syndrome that it is associated with, provides one of the best chances to understand the underlying mechanisms of autism," says Randall L. Rasmusson, PhD, professor of physiology and biophysics in the UB School of Medicine and Biomedical Sciences and co-author on the PNAS paper.
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